Speaker: Jin Ju Day: Wednesday, 11/10/2004 Room: ITE 336 Time: 3:30pm-4:30pm Title: Bayesian Methods for Haplotype Inference ---------------------------------------------------------------------------- Abstract: In this talk, application of Bayesian methods to haplotype inference will be shown. Haplotype inference is the problem of inferring original haplotype pairs from given genotypes, one of which can be explained by many possible haplotype pairs. Due to the hidden configurations (possible haplotype pairs per each genotype) and the exponentially growing size of these, traditional likelihood approach, e.g. MLE, is not efficient. To resolve this obstacle, an iterative optimization technique, Gibbs Sampling, is applied to this problems. Moreover, two algorithms are be showing with two different prior models. back to CSE-TS page