HealthGrid: Toward Collaborative and On-Demand Healthcare Modern grid technologies facilitate the coupling of geographically distributed resources and offer consistent and secure access irrespective of users' physical location or access point. This enables sharing, selection, and aggregation of a wide variety of distributed resources, such as supercomputers, storage systems, data sources, instruments, software systems, etc., and allows them to be used as a single, unified resource. This special issue focuses on the development, deployment and evaluation of grid technologies in health-related research and practice. Specifically, the special issue concentrates on all aspects of grid-enabled infrastructures, testbeds, management and security in support of the following health informatics areas: * Tele-systems for Diagnostic, Prognostic, and Therapeutic Applications * Health Data Storage & Retrieval * Biomedical Modeling and Simulation * Medical Imaging: Management, Analysis, Processing and Simulation * Distributed Medical Database Management and Integration * Integration of Health Information * Data Mining and Visualization of Medical Data * Text Mining of Medical Information Bases * Social Healthcare * Pharmaceutics and Clinical Trials * Computerized Epidemiology * Collaborative and Proprietary Health Grids * Integrative Bioinformatics and Medical Informatics Systems In addition to the focus areas, research articles reporting on original results of developing, deploying and evaluating grid techniques in broader health-related areas such as bioinformatics, clinical informatics, bioimaging, and public health informatics are also solicited. Prospective authors are welcome to discuss the issue scope with the editors before submitting their articles. Authors are referred to the general guidelines for manuscript formatting instructions available at the official JCMC website. Tentative submission deadline is March 31, 2005. Authors should submit their manuscripts as email attachments to huang@cse.uconn.edu. All submissions will be acknowledged and promptly reviewed. Guest Editors (in alphabetical order): Prof. Werner Dubitzky Professor of Bioinformatics School of Biomedical Sciences University of Ulster Northern Ireland Prof. Chun-Hsi Huang Assistant Professor Department of Computer Science and Engineering University of Connecticut Storrs, CT 06269 USA Dr. Vincenzo Lanza Chief of Anesthesiology Department OSPEDALE BUCCHERI LA FERLA FATEBENEFRATELLI VIA M.MARINE, 197 90123-PALERMO Italy Prof. Sanguthevar Rajasekaran UTC Professor Department of Computer Science and Engineering University of Connecticut Storrs, CT 06269 USA